6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
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Applications6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
SolubilitySoluble in dilute solutions of alkali hydroxides, hot alcohol, and 1 N NaOH (50 mg/ml). Insoluble in water.
NotesStore in cool, dry place, in well sealed container. Store away from oxidizing agents.