1,3,5-Tribromobenzene is used as an intermediate for active pharmaceutical ingredient manufacturing. It acts as an intermediate for the preparation of 1,3,5-trimethoxytoluene. It forms molecular complexes with [60]-and [70] fullerenes. Further, it is employed as an internal standard during derivatization step in the determination of cyanide in human plasma and urine by gas chromatography-mass spectrometry. In addition to this, it reacts with the perfluoroalkenylzinc reagent in the presence of tetrakis(triphenylphosphine)palladium catalyst to yield a trifunctional monomer 1,3,5-tris(alfa, beta, beta-trifluorovinyl)benzene.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1,3,5-Tribromobenzene is used as an intermediate for active pharmaceutical ingredient manufacturing. It acts as an intermediate for the preparation of 1,3,5-trimethoxytoluene. It forms molecular complexes with [60]-and [70] fullerenes. Further, it is employed as an internal standard during derivatization step in the determination of cyanide in human plasma and urine by gas chromatography-mass spectrometry. In addition to this, it reacts with the perfluoroalkenylzinc reagent in the presence of tetrakis(triphenylphosphine)palladium catalyst to yield a trifunctional monomer 1,3,5-tris(alfa, beta, beta-trifluorovinyl)benzene.
SolubilitySoluble in hot ethanol and acetic acid. Insoluble in water.
NotesIncompatible with strong oxidizing agents.