4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
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Applications4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
SolubilityInsoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).
NotesStable under recommended storage conditions. Incompatible with oxidizing agents and heat.