This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• β-Estradiol is a naturally occurring endogenous hormone in females
• It is an important steroid sex hormone involved in the regulation of several biological functions including gene transcription and protein synthesis
• This hormone is produced by the ovaries and can bind to and activate specific nuclear receptors
Applications
• β-Estradiol acts as an estrogenic hormone receptor agonist and activator of PI 3-kinase
• It shows inhibitory activity against aldehyde oxidase
• β-Estradiol presents mild anabolic and metabolic activities and increases blood coagulability in vivo experiments
• It plays a role in immune and inflammatory processes
• β-Estradiol triggers an increase in hepatic synthesis of some proteins, including sex hormone-binding globulin (SHBG), and thyroid-binding globulin (TBG), and suppresses the formation of follicle-stimulating hormone (FSH)
• This compound has been used for the in vitro maturation of bovine cumulus-oocyte complexes (COCs)