This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• L(+)-Amethopterin hydrate, is a potent inhibitor of dihydrofolate reductase
• It has tumoricidal activity
Applications
• L(+)-Amethopterin hydrate is an inhibitor of dihydrofolate reductase
• It can be used in anti-tumor studies
• It is a cell cycle arrest agent, which can inhibit synthesis of DNA, RNA, and proteins
• It can also inhibit production of pro-inflammatory cytokines