Immunogen sequence: AEQHLESPVP SAPGALAGGP TQAAPGVRGE EEQWAREIGA QLRRMADDLN AQYERRRQEE QQRHRPSPWR VLYNLIMGLL PLPRGHRAPE MEPN. PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The