Sequence homology: Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%. Defects in RPIA are the cause of ribose 5-phosphate isomerase deficiency. The exact function o