In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) IL-1F6 is observed, approximately 5% cross-reactivity with rhIL-1F7 is observed, and less than 1% cross-reactivity with rhIL-1 alpha, rhIL-1 beta, rhIL-1F5, and rhIL-1F8 is