In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) IL-1F8 is observed and less than 1% cross-reactivity with recombinant mouse (rm) IL-1 alpha, rmIL-1 beta, rmIL-1ra, rmIL-18, rhIL-1F5, rmIL-1F6, rhIL-1F7, rhIL-