Immunogen sequence: YPVTTIIAPP GHTGVACSCH QCLSGSRTGP VSGRYRHSMT NLPAYPVPQH PPHRTASVFG THQAFAPYNK PSL Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 75%. DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signal