Immunogen sequence: AQPESIRSDL ESSDAQSDDV PDITSDECGS PRSHTAACPS TPRAQGAPSP SAHMNLSALA EGQTVLKPEG GEA Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%. E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquit