Description: Staurosporine is a cell permeable inhibitor of protein kinases, including protein kinase-C. Inhibitor of nuclear factor kappa B kinase beta subunit.
Solubility ( literature ): DMSO, Methanol, Ethanol, Ethyl Acetate. Water insoluble
Applications: Pharmacological tool to study signal transduction pathways, tyrosine phosphorylation and to induce apoptosis. May participate in antigen-induced T-cell activation; Affects Proto-oncogene serine/threonine-protein kinase Pim-1, T-cell-specific kinase, Tyrosine-protein kinase SYK, MAP kinase-activated protein kinase 2
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: Synonyms: Antibiotic AM 2282; RTECS: KD5084000 ; attention: This RTECS record belongs to the Hydrochloride salt of Staurosporine, rather than the free base form.
Pub 1:
Source: Streptomyces staurosporeus
Chemical name: Staurosporine
InChl Key: HKSZLNNOFSGOKW-FYTWVXJKSA-N