Description: Brefeldin A is a macrocyclic lactone from fungal source, exhibiting a wide range of antibiotic activity.
Solubility ( literature ): Methanol, Ethanol, Dichloromethane, DMSO, acetone or ethyl acetate
Applications: Inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus. Inhibitor of intracellular protein transport and protein secretionA macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: Synonyms: Nectrolide Synergisidin Cyanaein Ascotoxin Cyanein Decumbin Brefeldin A EC# : 606-528-3 Systematic name: (1R,2E,6S,10E,11aS,13S,14aR)-1,13-Dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one RTECS: GY8410000
Pub 1:
Source: Eupenicillium brefeldianum
Chemical name:
InChl Key: KQNZDYYTLMIZCT-HHMYAMTESA-N