Description: Meleagrin, a fungal alcaloide antibiotic, posesses antitumor and antibiotic activity. Meleagrin has been identified as an inhibitor of the bacterial enoyl-acyl carrier protein reductase. Meleagrin, CAS 71751-77-4, the fungal alcaloide, should not be confused with the low molecular weight peptide cas 121272-63-7, which is isolated from turkey also called meleagrin.
Solubility ( literature ): Ethanol, methanol, DMF or DMSO. Poor water solubility
Applications: Inhibitor of: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: Synonyms: 6-O-Methyloxaline Chemical names: IUPAC: (3E,7aS,12aR)-6-hydroxy-3-(1H-imidazol-4-ylmethylidene)-12-methoxy-7a-(2-methylbut-3-en-2-yl)-7a,12-dihydro-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione RTECS#
Pub 1: J Antibiot (Tokyo). 2010 Apr;63(4):165-70. Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities. Du L, Feng T, Zhao B, Li D, Cai S, Zhu T, Wang F, Xiao X, Gu Q. -----
Source: Penicillium chrysogenum
Chemical name: Meleagrin
InChl Key: JTJJJLSLKZFEPJ-YVLHZVERSA-N