Description: PKC412 (Midostaurin) is a cell permeable inhibitor of protein kinases, including protein kinase-C.
Solubility ( literature ): Soluble in DMSO, Dichloromethane. Water solubility : < 0.1 mg/1
Applications: PKC412 is mentioned as a specific treatment for Myeloproliferative Disease (MPD) PKC412 selectively inhibits protein kinase C (PKC) Investigated for use/treatment in adult patients with high-risk acute myeloid leukemia (AML)
Composition: Ingredient type Fermentek product
Disclaimer: Semi-Synthetic.
Names and identifiers: Synonyms: Midostaurin PKC412 Benzoylstaurosporine 4'-N-Benzoylstaurosporine Commercial names: Rydapt RTECS: CV5045180
Pub 1:
Source: Synthetic
Chemical name: 4'-N-benzoyl staurosporine
InChl Key: BMGQWWVMWDBQGC-UHFFFAOYSA-N