This antibody reacts with 30% of IgM-RF from unrelated individuals. It does not recognize IgM, IgA, or IgG proteins lacking RF nor with F(ab')2 fragments. Antibodies directed against the Fc fragment of immunoglobulin G (IgG) are called rheumatoid factors
This antibody reacts with 30% of IgM-RF from unrelated individuals. It does not recognize IgM, IgA, or IgG proteins lacking RF nor with F(ab')2 fragments. Antibodies directed against the Fc fragment of immunoglobulin G (IgG) are called rheumatoid factors
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