Description: Aloe-emodin is a hydroxyanthraquinone found naturally in Aloe vera and in other aloe plants. It exhibits antibacterial, antiviral, anti-inflammatory and hepatoprotective effects. recently it gains interest as a candidate anti-cancer agent.
Solubility ( literature ):
Applications: Aloe-emodin is a drug candidate for cancer therapy. It induces apoptosis in human oral squamous cell carcinoma SCC15 cells ; It exerts potent anticancer effects in MIAPaCa-2 and PANC-1 human pancreatic adenocarcinoma cell lines through activation of both apoptotic and autophagic pathways, sub-G1 cell cycle arrest and disruption of mitochondrial membrane potential It induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: Synonyms: * Aloe-emodin * 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- * 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione * 1,8-Dihydroxy-3-hydroxymethylanthraquinone * 3-Hydroxymethylchrysazin * Rhabarberone RTECS : CB6712200
Pub 1: Oncotarget, 2018, Vol 9, (No 25) pp: 17770-17796 Aloe-emodin as drug candidate for cancer therapy Nadire Ozenver, Mohamed Saeed, Lutfiye Omur Demirezer, Thomas Efferth
Source: Aloe Vera (extracted from plant)
Chemical name:
InChl Key: YDQWDHRMZQUTBA-UHFFFAOYSA-N