Description: Blasticidin S Hydrochloride belongs to a group of cytosine amino nucleoside antibiotics. The compound Blasticidin S has a wide spectrum of antimicrobial activity and acts on prokaryotic and eukaryotic organisms by inhibiting protein synthesis.
Solubility ( literature ): Soluble in water, Acetic acid. Slightly soluble in acidified methanol.
Applications: Blasticidin-S is a commonly used tool in genetic engineering. Blasticidin-S inhibits protein synthesis in both prokaryotic and eukaryotic cells. It is common method to include a gene for Blasticidin S resistance into the plasmid being inserted into the target cells, and then to apply Blasticidin S to the culture to select these cells that have acquired that immunity. The Blasticidin S gene resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Another antibiotic that belongs to the family of nucleosides is Puromycin.
Composition: Ingredient type Fermentek product
Disclaimer: Refer to MSDS for further safety and handling instructions.
Names and identifiers: Synonyms: Bla-S Blasticidin S, monohydrochloride (8CI) IUPAC Name: (2S,3S, 6R)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylicacid; hydrochloride RTECS: EC4900000
Pub 1:
Source: Streptomyces griseochromogenes
Chemical name:
InChl Key: YQXYQOXRCNEATG-ZAYJLJTISA-N