Description: Cyclic tetrapeptide of structure cyclo(D-Pro-L-Ala-D-Ala-L-Aeo), where Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid. HC toxin is a potent, cell-permeable inhibitor of histone deacetylase (HDAC).
Solubility ( literature ):
Applications:
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: Synonyms: HC-Toxin Helminthosporium Carbonum Toxin I Chemical names: IUPAC: (3S,6R,9S,14aR)-3,6-Dimethyl-9-{6-[(2S)-2-oxiranyl]-6-oxohexyl}decahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetrone RTECS#
Pub 1: The Plant Cell, Vol. 7, 1941-1950, November 1995 O 1995 American Society of Plant Physiologists Gerald Broschla Richard Ransom,b Thomas Lechnerla Jonathan D. Walton and Peter Loidlai lnhibition of Maize Histone Deacetylases by HC Toxin, the Host-Selective Toxin of Cochliobolus carbonum
Source: Helminthosporium carbonum
Chemical name: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine)
InChl Key: GNYCTMYOHGBSBI-KVUCBBCISA-N