Description: Cyclic hexapeptide antibiotic. Phomopsin A exhibits very strong inhibitory properties of microtubule assembly. It binds to tubulin at a site different from the colchicine binding site.
Solubility ( literature ): Soluble in Ethanol, DMSO and DMF. Sparingly siluble in water. Not stable in watery solutions. (lit).
Applications:
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: IUPAC: (2E)-2-{[(2E)-2-({[(2S)-1-{[(3R,4S,7S,10S,11S)-14-Chloro-3-ethyl-11,15-dihydroxy-7-isopropenyl-3-methyl-10-(methylamino)-6,9-dioxo-2-oxa-5,8-diazabicyclo[10.3.1]hexadeca-1(16),12,14-trien-4-yl]carbony l}-2,5-dihydro-1H-pyrrol-2-yl]carbonyl}amino)-3-methyl-2-pentenoyl]amino}-2-butenedioic acid RTECS# SY2593000
Pub 1:
Source: Phomopsis leptostromiformis
Chemical name: Phomopsin A
InChl Key: FAFRRYBYQKPKSY-AJSRVUJESA-N