Description: Type D trichothecene, exhibiting anti-cancer properties
Solubility ( literature ):
Applications:
Composition: Ingredient type Fermentek product
Disclaimer: For Research use only, Not for Human or Drug use, Not extracted from humans or animals, Refer to MSDS for further safety and handling instructions
Names and identifiers: Synonyms: Verrucarin J Verrucarin A, 2',3'-didehydro-2'-deoxy-, (2'E)-(2'E)-2',3'-Didehydro-2'-deoxyverrucarin Muconomycin B Verrucrin J Verrucosporin J Chemical names: Verrucarin A, 2',3'-didehydro-2'-deoxy- IUPAC: (1'R,3'R,8'R,12'E,18'E,20'Z,24'R,25'S)-5',13',25'-Trimethyl-11'H,17'H,22'H-spiro[oxirane-2,26'-[2,10,16,23]tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa[4,12,18,20]tetraene]-11',17',22'-trione RTECS# YX9822000
Pub 1: Kelsey Carter, Pranela Rameshwar, Mariusz Z. Ratajczak, Sham S. Kakar Oncotarget. 2017 Nov 3; 8(54): 92743–92756. Verrucarin J inhibits ovarian cancer and targets cancer stem cells PMCID: PMC5696218 PMID: 29190952 -------- Udoh K, Parte S, Carter K, Mack A, Kakar SS. Stem Cell Rev Rep. 2019 Aug;15(4):601-611. doi: 10.1007/s12015-019-09874-7. Targeting of Lung Cancer Stem Cell Self-Renewal Pathway by a Small Molecule Verrucarin J PMID: 30835047 PMCID: PMC6626573 --------
Source: Myrothecium sp.
Chemical name: Verrucarin A, 2',3'-didehydro-2'-deoxy-
InChl Key: GXCGYHWSYNQVHU-UGAPSZEOSA-N