Immunogen sequence: REEVHTMLRG VLFFSTPRTF QEMIQRLYGC FLRVYMQSKR KGEGGTDPEL EGELDSRYAR RRYYRLLQSP LCAGCSSDKQ QCWCR. A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitin